SCHEMBL10746567

SCHEMBL10746567

O=C(NC(=O)c1ccc(F)cc1Cl)Nc1ccc(Oc2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PYGL P06737 10/20 0.64
GCGR P47871 1/20 0.61
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
PNLIP P16233 1/20 0.57
SCN8A Q9UQD0 2/20 0.56
SCN10A Q9Y5Y9 2/20 0.56
STK39 Q9UEW8 1/20 0.55
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
ALOX12 P18054 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10747451 0.86 PYGL (0.58) PYGLGCGRNPC1RAB9APNLIP
SCHEMBL10746618 0.83 PYGL (0.76) PYGLNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL10746092 0.80 PYGL (0.58) PYGLGCGRNPC1RAB9AALDH1A1
SCHEMBL10746663 0.79 GCGR (0.55) PYGLGCGRNPC1RAB9APNLIP
SCHEMBL10744999 0.78 PYGL (0.55) PYGLGCGRPNLIPSCN8ASCN10A
SCHEMBL10750167 0.78 GCGR (0.54) PYGLGCGRNPC1RAB9APNLIP
SCHEMBL10646104 0.78 PYGL (0.68) PYGLNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL10749067 0.77 PYGL (0.52) PYGLGCGRNPC1RAB9AMAPT
SCHEMBL11839436 0.77 MAPT (0.77) GCGRNPC1PNLIPSTK39ALDH1A1
SCHEMBL1514346 0.77 GCGR (0.60) PYGLGCGRNPC1RAB9APNLIP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4711905-A 2,4-dihalogenobenzoyl-(thio)urea insecticides BAYER AKTIENGESELLSCHAFT (DE) 1987-12-08 US claimed