Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657600 | 0.83 | MEN1 (0.52) | PYGLKMT2AMEN1GAAPKM | |
| SCHEMBL10744999 | 0.82 | PYGL (0.55) | PYGLGCGR | |
| SCHEMBL11832824 | 0.79 | KMT2A (0.61) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL10746567 | 0.77 | PYGL (0.64) | PYGLMAPTRAB9ASMN1; SMN2GCGR | |
| SCHEMBL9688240 | 0.77 | MAPT (0.60) | PYGLKMT2AMEN1GAAMAPT | |
| SCHEMBL11832770 | 0.77 | KMT2A (0.57) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL11839070 | 0.77 | KMT2A (0.57) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL11836660 | 0.75 | KMT2A (0.55) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL9135999 | 0.75 | GCGR (0.58) | PYGLKMT2AMEN1GAAPKM | |
| SCHEMBL11824796 | 0.74 | KMT2A (0.54) | KMT2AMEN1GAAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711905-A | 2,4-dihalogenobenzoyl-(thio)urea insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | claimed |