Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LIPA | P38571 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796363 | 0.79 | TDP1 (0.56) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL8793041 | 0.79 | TDP1 (0.56) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL10993216 | 0.79 | TDP1 (0.56) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL30673515 | 0.77 | CYP1A2 (0.67) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL9393155 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL11127560 | 0.73 | CYP1A2 (0.64) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL10635041 | 0.73 | CYP1A2 (0.64) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL17244724 | 0.72 | ALDH1A1 (1.00) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL29173854 | 0.72 | KMT2A (0.54) | KMT2AALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL18908562 | 0.72 | CYP1A2 (0.71) | KMT2AALDH1A1MAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221806-A1 | Substituted thiophene-2-sulfanomide and antiglaucoma compositions containing them | MERCK & CO. INC. (US) | 1987-05-13 | — | — | EP | disclosed |