Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | LIPA | P38571 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078250 | 0.81 | LIPA (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL17078300 | 0.78 | LIPA (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL17078227 | 0.76 | LIPA (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL17078235 | 0.75 | LIPA (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL19607575 | 0.75 | LIPA (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL22799434 | 0.74 | ABHD6 (1.00) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL30673515 | 0.73 | CYP1A2 (0.67) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL13953865 | 0.73 | KMT2A (0.69) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL10749130 | 0.72 | KMT2A (0.58) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9817959 | 0.71 | CYP1A2 (0.63) | ALDH1A1MAPTKDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329542-B2 | HBV RNAse H purification and enzyme inhibitors | SAINT LOUIS UNIVERSITY (US) | 2019-06-25 | — | — | US | disclosed |
| US-20170335296-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | SAINT LOUIS UNIVERSITY (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170335296-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | SAINT LOUIS UNIVERSITY (US) | 2017-11-23 | — | — | US | disclosed |
| US-20150322413-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | SAINT LOUIS UNIVERSITY (US) | 2015-11-12 | — | — | US | disclosed |
| US-20150322413-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | SAINT LOUIS UNIVERSITY (US) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170335296-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | RNASEH1, RNASE1, RNASEL | ALDH1A1 2477/4885MAPT 4504/4885KDM4E 3174/4885 |
| US-20150322413-A1 | HBV RNASE H PURIFICATION AND ENZYME INHIBITORS | RNASEH1, RNASE1, RNASEL | ALDH1A1 2477/4885MAPT 4504/4885KDM4E 3174/4885 |
| US-10329542-B2 | HBV RNAse H purification and enzyme inhibitors | RNASEH1, RNASE1, RNASEL | ALDH1A1 2477/4885MAPT 4504/4885KDM4E 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.