Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.59 |
| ▸ | DHODH | Q02127 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 5/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147282 | 0.87 | CES2 (0.68) | CES2CES1TDP1L3MBTL1CYP2C19 | |
| SCHEMBL11315479 | 0.81 | KMO (0.67) | KMODHODHCES2CES1HDAC8 | |
| SCHEMBL10416725 | 0.81 | DHODH (0.46) | KMODHODHPRSS1PRSS2PRSS3 | |
| SCHEMBL16108338 | 0.78 | KMO (0.69) | KMODHODHCES2CES1PRSS1 | |
| Benzoic Acid SCHEMBL27510212 | 0.78 | KMO (0.83) | KMODHODHCES2CES1HDAC8 | |
| Benzoic Acid SCHEMBL27844190 | 0.78 | KMO (0.68) | KMODHODHPRSS1PRSS2PRSS3 | |
| SCHEMBL29788172 | 0.77 | DHODH (0.70) | KMODHODHPRSS1PRSS2PRSS3 | |
| SCHEMBL43553 | 0.77 | DHODH (0.70) | KMODHODHPRSS1PRSS2PRSS3 | |
| Butane SCHEMBL11583778 | 0.77 | CES2 (0.59) | CES2CES1TDP1L3MBTL1CYP2C19 | |
| Urea SCHEMBL12500731 | 0.77 | KMO (0.52) | KMODHODHPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025842-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |