Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.72 |
| ▸ | DRD4 | P21917 | 4/20 | 0.72 |
| ▸ | CCR3 | P51677 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 8/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720274 | 1.00 | DRD2 (0.72) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10723885 | 1.00 | DRD2 (0.72) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10720221 | 1.00 | DRD2 (0.72) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10723842 | 1.00 | DRD2 (0.72) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL7132544 | 0.98 | DRD2 (0.74) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10723691 | 0.97 | ALDH1A1 (0.72) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10720845 | 0.94 | ALDH1A1 (0.76) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL10723851 | 0.92 | SIGMAR1 (0.64) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL7391346 | 0.91 | CCR3 (0.64) | DRD2DRD4CCR3DRD3HTR1A | |
| SCHEMBL7381097 | 0.91 | CCR3 (0.64) | DRD2DRD4CCR3DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |