Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569327 | 0.87 | FAAH (0.51) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL28176966 | 0.82 | FAAH (0.48) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL9589828 | 0.76 | NPSR1 (0.49) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL15205509 | 0.76 | TSHR (0.56) | GAAMAPTALDH1A1POLBTSHR | |
| SCHEMBL4194016 | 0.75 | GAA (0.40) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL4794056 | 0.74 | KMT2A (0.45) | FAAHNAAANPSR1NPC1RAB9A | |
| SCHEMBL11370007 | 0.74 | NAAA (0.77) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL6219776 | 0.72 | LMNA (0.50) | RAB9AMAPTALDH1A1POLBTSHR | |
| SCHEMBL11372041 | 0.72 | FAAH (0.64) | FAAHNAAANPSR1HSD17B10GAA | |
| SCHEMBL4511304 | 0.71 | MAPK1 (0.46) | FAAHNAAANPSR1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220435-A1 | A method for preparing optically active half esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-06 | — | — | EP | disclosed |