Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751196 | 0.83 | ALDH1A1 (0.50) | GSK3BALDH1A1 | |
| SCHEMBL10754025 | 0.80 | KDM4E (0.43) | ALDH1A1MAPTELANE | |
| SCHEMBL10751737 | 0.80 | LMNA (0.43) | GSK3BALDH1A1MAPT | |
| SCHEMBL10755815 | 0.80 | HTT (0.52) | ALDH1A1MAPTELANE | |
| SCHEMBL10755526 | 0.80 | MAPT (0.46) | NR3C1GAAALDH1A1MAPTELANE | |
| SCHEMBL10755186 | 0.80 | MAPT (0.49) | NR3C1GAAALDH1A1MAPT | |
| SCHEMBL11603257 | 0.79 | HTT (0.51) | ALDH1A1MAPTELANE | |
| SCHEMBL10753219 | 0.78 | SRD5A2 (0.47) | GAAALDH1A1PKMMAPTELANE | |
| SCHEMBL10757879 | 0.78 | LMNA (0.46) | GSK3BCA1CA2GAAALDH1A1 | |
| SCHEMBL10758063 | 0.77 | L3MBTL1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687858-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4508910-A | Herbicidal 4-benzoyl-5-hydroxy-pyrazales | SANKYO COMPANY LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| US-4414392-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |