SCHEMBL1075162

SCHEMBL1075162

O=C1OCC2CC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13309236 1.00
SCHEMBL3387123 1.00
SCHEMBL14435544 1.00
SCHEMBL21396628 0.87
SCHEMBL6357085 0.87
SCHEMBL13451412 0.84
SCHEMBL6692240 0.84 KDM4E (0.32)
SCHEMBL21185140 0.84
SCHEMBL851839 0.80
SCHEMBL21787940 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10059955-A None JP disclosed
CN-115304568-B Asymmetric synthesis method of 6-azidomethylene-1-aryl-3-oxabicyclo [3,1,0] hex-2-one 扬州大学 2024-03-26 CN disclosed
EP-4322954-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT Merck Sharp & Dohme LLC (US) 2024-02-21 EP disclosed
CN-115304568-A Asymmetric synthesis method of 6-azidomethylene-1-aryl-3-oxabicyclo [3,1,0] hexan-2-ketone 扬州大学 2022-11-08 CN disclosed
WO-2022221739-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT MERCK SHARP & DOHME CORP. (US) 2022-10-20 WO disclosed
CN-114805167-A Preparation method of brivaracetam 上海博志研新药物技术有限公司 2022-07-29 CN disclosed
WO-2018107056-A1 1,3-SUBSTITUED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACIC LEVELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2018-06-14 WO disclosed
US-9595734-B2 Non-aqueous liquid electrolyte for secondary battery and secondary battery FUJIFILM CORPORATION (JP) 2017-03-14 US disclosed
US-9595734-B2 Non-aqueous liquid electrolyte for secondary battery and secondary battery FUJIFILM CORPORATION (JP) 2017-03-14 US disclosed
US-20140234729-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed
WO-2006048152-A2 DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2006-05-11 WO disclosed
EP-1080085-A1 PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO 3.1.0]HEXAN-2-ONE ZENECA LIMITED (GB) 2001-03-07 EP disclosed
WO-1999054324-A1 PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO[3.1.0]HEXAN-2-ONE ZENECA LIMITED (GB) 1999-10-28 WO disclosed
JP-H1059955-A 2-OXO-3-OXIBICYCLO(3,1,0)HEXANE DERIVATIVE AND ITS PRODUCTION DAISO CO LTD 1998-03-03 JP disclosed
US-4720556-A 3-oxabicyclo-(3,1,0)-hexan-2-ones ROUSSEL UCLAF (FR) 1988-01-19 US disclosed
US-4398032-A REDUCTION WITH SELECTIVE REDUCING AGENT SHELL OIL COMPANY (US) 1983-08-09 US disclosed
US-4375557-A REDUCTION OF DIHALO-OXABICYCLO(3.1.0)HEXAN-2-ONE SHELL OIL COMPANY (US) 1983-03-01 US disclosed
US-4346038-A Oxabicyclo[3.1.0]hexan-2-ones SHELL OIL COMPANY (US) 1982-08-24 US disclosed
US-4346038-A Oxabicyclo[3.1.0]hexan-2-ones SHELL OIL COMPANY (US) 1982-08-24 US disclosed
EP-0004493-A1 Ethers whose organic moieties have asymmetric atoms, methods for their preparation and their use for the resolution of alcohols, phenols or certain compounds with a lactone structure ROUSSEL-UCLAF (FR) 1979-10-03 EP disclosed