⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075162 | 1.00 | — | — | |
| SCHEMBL13309236 | 1.00 | — | — | |
| SCHEMBL3387123 | 1.00 | — | — | |
| SCHEMBL21396628 | 0.87 | — | — | |
| SCHEMBL6357085 | 0.87 | — | — | |
| SCHEMBL13451412 | 0.84 | — | — | |
| SCHEMBL6692240 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL21185140 | 0.84 | — | — | |
| SCHEMBL851839 | 0.80 | — | — | |
| SCHEMBL21787940 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924140-A | Preparation method of buvaracetam and intermediate thereof | 浙江工业大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115340482-A | Synthesis method of brivaracetam | 四川诺非特生物药业科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-112062740-B | Synthesis method of (R) -4-propyl dihydrofuran-2-ketone | 深圳市华先医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-112062740-B | Synthesis method of (R) -4-propyl dihydrofuran-2-ketone | 深圳市华先医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2013168002-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | KANDULA MAHESH (IN) | 2013-11-14 | — | — | WO | disclosed |
| WO-2007098356-A1 | CONGENERS OF MILNACIPRAN AS MONOAMINE RE-UPTAKE | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |