Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747845 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAANPC1RAB9AMAPT | |
| SCHEMBL29915528 | 0.74 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL1242243 | 0.74 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL11642669 | 0.73 | ALDH1A1 (0.62) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL27841975 | 0.72 | ALDH1A1 (0.68) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL6770549 | 0.71 | HPGD (0.59) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL3251235 | 0.71 | ALDH1A1 (0.52) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL3481961 | 0.71 | RAB9A (0.62) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL16469103 | 0.71 | L3MBTL1 (0.44) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL6665398 | 0.70 | ALDH1A1 (0.59) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699652-A | Fungicidal pyridine derivatives for use in agriculture | HOFFMANN-LA ROCHE INC. (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0209854-A2 | Pyridine derivatives and their use as fungicidal agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-01-28 | — | — | EP | disclosed |