SCHEMBL10752170

SCHEMBL10752170

C=C(CS)C(=O)Oc1ccc2ccccc2c1N(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 14/20 0.45
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10750357 0.81 HPGD (0.41) NCEH1LMNASMN1; SMN2RAB9ANPC1
SCHEMBL10752164 0.80 NCEH1 (0.44) NCEH1LMNASMN1; SMN2RAB9ANPC1
SCHEMBL4830574 0.80 ALDH1A1 (0.51) RAB9AMAPTALDH1A1TSHRHSD17B10
SCHEMBL10752270 0.78 WDR5 (0.40) NCEH1LMNASMN1; SMN2RAB9ANPC1
SCHEMBL10752177 0.75 NCEH1 (0.43) NCEH1LMNASMN1; SMN2RAB9ANPC1
SCHEMBL10748366 0.73 TSHR (0.45) LMNASMN1; SMN2RAB9ANPC1MAPT
SCHEMBL22965399 0.71 MAPT (0.60) NCEH1LMNASMN1; SMN2RAB9AMAPT
SCHEMBL1336289 0.68 ALDH1A1 (0.55) RAB9AALDH1A1TSHRHSD17B10
SCHEMBL544812 0.68 ELANE (0.45) MAPTALDH1A1HSD17B10
SCHEMBL3821942 0.67 CYP1B1 (0.45) NCEH1LMNASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4654431-A Photopolymerizable thioacrylate monomers EASTMAN KODAK COMPANY (US) 1987-03-31 US disclosed