Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758022 | 0.84 | ADORA3 (0.49) | ADORA1ADORA3ADORA2AALDH1A1HPGD | |
| SCHEMBL10752938 | 0.80 | TOP1 (0.42) | ADORA1ADORA3ADORA2AALDH1A1HPGD | |
| SCHEMBL11846851 | 0.77 | LMNA (0.44) | SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL11840844 | 0.73 | PARP1 (0.36) | ADORA3ADORA2AL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL10756788 | 0.72 | ADORA3 (0.38) | ADORA1ADORA3ADORA2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10751428 | 0.72 | ABCG2 (0.43) | ADORA1ADORA3ADORA2AHPGDKMT2A | |
| SCHEMBL4663088 | 0.72 | MAPK1 (0.49) | ADORA1ADORA3ADORA2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10756143 | 0.72 | ACP1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL10753803 | 0.72 | ABCG2 (0.60) | ADORA1ADORA3ADORA2A | |
| SCHEMBL10758608 | 0.69 | PARP1 (0.46) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | disclosed |
| US-3947434-A | 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-30 | — | — | US | disclosed |