Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752944 | 0.84 | ADORA1 (0.50) | ADORA3ADORA2AADORA1ESR1ESR2 | |
| SCHEMBL11829399 | 0.76 | PDE3B (0.36) | QPCTQPCTLKDM4EMAPTKMT2A | |
| SCHEMBL11840840 | 0.72 | MAP4K4 (0.33) | QPCTQPCTL | |
| Hydrochloric Acid SCHEMBL10751428 | 0.71 | ABCG2 (0.43) | ADORA3ADORA2AADORA1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL10756788 | 0.71 | ADORA3 (0.38) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10753803 | 0.71 | ABCG2 (0.60) | ADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL11844430 | 0.70 | ALDH1A1 (0.47) | ADORA3ADORA2AADORA1ESR1ESR2 | |
| SCHEMBL10611217 | 0.70 | SMN1; SMN2 (0.46) | IDO1TDO2ESR1ESR2KDM4E | |
| SCHEMBL1520970 | 0.69 | QPCT (0.40) | QPCTQPCTLKDM4EMAPTALDH1A1 | |
| SCHEMBL10756075 | 0.68 | PARP1 (0.35) | QPCTQPCTLKDM4EMAPTMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | disclosed |
| US-3947434-A | 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-30 | — | — | US | disclosed |