Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754099 | 0.84 | HTR2A (0.44) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10754767 | 0.83 | GAA (0.42) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL18235618 | 0.80 | KMT2A (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10756653 | 0.79 | HTR1D (0.39) | SRCMAPTMEN1KMT2ALMNA | |
| SCHEMBL18222538 | 0.77 | HTR1A (0.41) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL15092407 | 0.76 | ALDH1A1 (0.44) | MAPTPRMT5WDR77RAB9AALDH1A1 | |
| SCHEMBL15092409 | 0.76 | ALDH1A1 (0.44) | MAPTPRMT5WDR77RAB9AALDH1A1 | |
| SCHEMBL12279346 | 0.76 | ALDH1A1 (0.44) | MAPTPRMT5WDR77RAB9AALDH1A1 | |
| SCHEMBL8913853 | 0.74 | GAA (0.73) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10758547 | 0.74 | HTR2A (0.65) | CCKBRSRCHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636521-A | ANALGESICS | GLAXO GROUP LIMITED (GB) | 1987-01-13 | — | — | US | disclosed |