Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752980 | 0.83 | CCKBR (0.46) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL10754099 | 0.81 | HTR2A (0.44) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL18235618 | 0.77 | KMT2A (0.40) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL9828298 | 0.76 | GAA (0.69) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL10756653 | 0.76 | HTR1D (0.39) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL10746246 | 0.74 | MAPT (0.70) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL18222538 | 0.74 | HTR1A (0.41) | GAAMEN1MAPTKMT2ALMNA | |
| SCHEMBL5239895 | 0.73 | HTR2A (0.48) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL20078269 | 0.73 | GUSB (0.50) | GAAMGAMSIMGAM2GUSB | |
| SCHEMBL14017318 | 0.73 | MAPT (0.65) | GAAMEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636521-A | ANALGESICS | GLAXO GROUP LIMITED (GB) | 1987-01-13 | — | — | US | disclosed |