Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753337 | 1.00 | CES2 (0.43) | CES2CES1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL11034197 | 0.78 | ALDH1A1 (0.39) | CES2CES1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL3680605 | 0.78 | CES2 (0.41) | CES2CES1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3680608 | 0.78 | CES2 (0.41) | CES2CES1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3680333 | 0.77 | CES2 (0.47) | CES2CES1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3680287 | 0.77 | CES2 (0.47) | CES2CES1ALDH1A1MAPTHTT | |
| SCHEMBL3680288 | 0.77 | CES2 (0.47) | CES2CES1ALDH1A1MAPTHTT | |
| SCHEMBL3680330 | 0.77 | CES2 (0.47) | CES2CES1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11823068 | 0.76 | CES2 (0.43) | CES2CES1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7535407 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4648895-A | ANTIDOTES | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |