Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938391 | 0.78 | USP2 (0.69) | USP2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL4963671 | 0.76 | USP2 (0.68) | USP2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL5160857 | 0.72 | ERCC5 (0.56) | USP2ERCC5FEN1ALDH1A1NPC1 | |
| SCHEMBL3455402 | 0.72 | USP2 (0.79) | USP2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17318734 | 0.70 | USP2 (0.49) | USP2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL17285675 | 0.69 | CES2 (0.55) | USP2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL22080098 | 0.69 | ALDH1A1 (0.56) | USP2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL10755506 | 0.68 | DAO (0.57) | USP2DAOERCC5FEN1ALDH1A1 | |
| Thiophene Carboxylic Acid SCHEMBL27740309 | 0.68 | DAO (0.76) | DAOERCC5FEN1ALDH1A1NPC1 | |
| SCHEMBL10441460 | 0.68 | DAO (0.57) | DAOERCC5FEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663329-A | Thienopyridinone derivatives and anti-bacterial compositions containing them | SANOFI (FR) | 1987-05-05 | — | — | US | disclosed |