Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938391 | 0.98 | USP2 (0.69) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL3455402 | 0.84 | USP2 (0.79) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL17285675 | 0.81 | CES2 (0.55) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL27284450 | 0.81 | USP2 (0.55) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL23386742 | 0.80 | USP2 (0.54) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL18413785 | 0.79 | USP2 (0.52) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL5160857 | 0.77 | ERCC5 (0.56) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL30038588 | 0.77 | ALDH1A1 (0.51) | USP2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL827527 | 0.76 | CES2 (0.64) | USP2ALDH1A1RAB9ANPC1CES2 | |
| SCHEMBL10754142 | 0.76 | USP2 (0.50) | USP2ALDH1A1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904472-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010954-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-01-25 | — | — | WO | disclosed |