Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751500 | 0.87 | NPSR1 (0.32) | DPP4NPSR1 | |
| SCHEMBL10750795 | 0.76 | NPSR1 (0.34) | DPP4HRH3HRH2NPSR1 | |
| SCHEMBL10751966 | 0.75 | DPP4 (0.33) | DPP4 | |
| SCHEMBL10751216 | 0.74 | DRD2 (0.35) | NPSR1 | |
| SCHEMBL768366 | 0.73 | UGT2B17 (0.57) | DPP4NPSR1UGT2B17 | |
| SCHEMBL10749309 | 0.73 | DPP4 (0.34) | DPP4 | |
| SCHEMBL23813210 | 0.70 | UGT2B17 (0.41) | DPP4NPSR1UGT2B17 | |
| SCHEMBL769214 | 0.70 | NOS3 (0.35) | DPP4NPSR1 | |
| SCHEMBL10751929 | 0.70 | ADRA1A (0.40) | — | |
| SCHEMBL10752770 | 0.69 | NPSR1 (0.36) | DPP4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634705-A | Adrenergic amidines | ABBOTT LABORATORIES (US) | 1987-01-06 | — | — | US | disclosed |