SCHEMBL10754755

SCHEMBL10754755

O=C1CC(OC2CC(=O)NC2=O)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.48
CRBN Q96SW2 8/20 0.40
DDB1 Q16531 7/20 0.37
CYP19A1 P11511 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34
NPC1 O15118 1/20 0.33
IDO1 P14902 3/20 0.32
GLA P06280 1/20 0.32
MEN1 O00255 1/20 0.32
APEX1 P27695 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8348991 0.84 MAP3K14 (0.48) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL1034864 0.80
SCHEMBL4985328 0.80
SCHEMBL2540971 0.77 MAP3K14 (0.41) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL1521456 0.77 MAP3K14 (0.41) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL3949247 0.75 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL9510783 0.75 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL7264550 0.75 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL10913393 0.75 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL2782193 0.73 MEN1 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212673-A2 Photographic paper FUJI PHOTO FILM CO., LTD. (JP) 1987-03-04 EP disclosed