SCHEMBL1521456

SCHEMBL1521456

O=[C]OC1CC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.41
CRBN Q96SW2 2/20 0.34
DDB1 Q16531 1/20 0.33
CYP19A1 P11511 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10754755 0.77 MAP3K14 (0.48) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL8348991 0.77 MAP3K14 (0.48) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL1034864 0.73
SCHEMBL4985328 0.73
SCHEMBL11339024 0.71
SCHEMBL2540971 0.70 MAP3K14 (0.41) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL7264550 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL3949247 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL9510783 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL10913393 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054933-B1 CHEMILUMINESCENT REACTIONS USING DIHYDROXYAROMATIC COMPOUNDS AND HETEROCYCLIC ENOL PHOSPHATES LUMIGEN INC (US) 2006-09-06 EP claimed
US-7071265-B2 Copolymerization of N-acryloxysuccinimide or N-methacryloxy-succinimide with methyl methacrylate, in the presence activators, solvents and stabilizer agents to form narrow particle size distribution copolymers FUJI XEROX CO., LTD. (JP) 2006-07-04 US claimed
US-6969742-B2 Method of producing a functional polymer particle FUJI XEROX CO., LTD. (JP) 2005-11-29 US claimed
US-6914100-B2 Method of producing a crosslinked polymer particle FUJI XEROX, CO., LTD. (JP) 2005-07-05 US claimed
US-6747160-B2 CAPABLE OF INDUCING CHEMILUMINESCENCE; SUBSTRATES FOR IMMUNOASSAY; STABLE; LOW BACKGROUND FOR MEASUREMENT TO PRESENT HIGH SENSITIVITY TOSOH CORPORATION (JP) 2004-06-08 US claimed
US-20040039109-A1 Method of producing a functional polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-26 US claimed
US-20040034171-A1 Method of producing a non-crosslinked polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-19 US claimed
US-20040034174-A1 Method of producing a crosslinked polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-19 US claimed
EP-1054933-A4 CHEMILUMINESCENT REACTIONS USING DIHYDROXYAROMATIC COMPOUNDS AND HETEROCYCLIC ENOL PHOSPHATES LUMIGEN INC (US) 2003-07-09 EP claimed
EP-0583820-B1 Novel carbamazepine hapten analogues JOHNSON & JOHNSON CLIN DIAG (US) 2002-03-20 EP claimed
US-5149416-A Water soluble, crosslinked acrylamide bases copolymer EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
EP-0502594-A1 Chelates, their metal complexes as well as their use in diagnosis and therapy INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) 1992-09-09 EP claimed
EP-0502595-A2 Amide chelates, their metal complexes and their use in diagnosis and therapy INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) 1992-09-09 EP claimed
EP-0496472-A1 Succinimide containing polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP claimed
EP-0496473-A2 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP claimed
WO-1992008494-A2 TARGETING RADIOACTIVE IMMUNOREAGENTS STERLING WINTHROP INC. (US) 1992-05-29 WO claimed
EP-0460026-A1 HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY COLUMN COMPRISING NON-POROUS, MONODISPERSE POLYMERIC PACKING MATERIAL EASTMAN KODAK COMPANY (US) 1991-12-11 EP claimed
WO-1990009832-A1 HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY COLUMN COMPRISING NON-POROUS, MONODISPERSE POLYMERIC PACKING MATERIAL EASTMAN KODAK COMPANY (US) 1990-09-07 WO claimed
EP-0071926-B1 NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-10-08 EP claimed
EP-0071926-A1 New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP claimed