SCHEMBL2540971

SCHEMBL2540971

O=COC1CC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.41
CRBN Q96SW2 2/20 0.34
DDB1 Q16531 1/20 0.33
CYP19A1 P11511 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10754755 0.77 MAP3K14 (0.48) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL8348991 0.77 MAP3K14 (0.48) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL4985328 0.73
SCHEMBL1034864 0.73
SCHEMBL3998968 0.73 CRBN (0.42) MAP3K14CRBN
SCHEMBL15270425 0.71
SCHEMBL18015890 0.69 MAP3K14 (0.38) MAP3K14CRBNDDB1CYP19A1GAA
SCHEMBL3949247 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL7264550 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA
SCHEMBL9510783 0.68 MAP3K14 (0.40) MAP3K14CRBNDDB1CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250180990-A1 PHOTOSENSITIVE SURFACE TREATING AGENT, LAMINATE, PATTERN FORMATION SUBSTRATE, TRANSISTOR, PATTERN FORMING METHOD AND METHOD OF PRODUCING TRANSISTOR NIKON CORPORATION (JP) 2025-06-05 US disclosed
WO-2024043222-A1 PHOTOSENSITIVE SURFACE TREATMENT AGENT, LAMINATE, SUBSTRATE FOR PATTERN FORMATION, TRANSISTOR, PATTERN FORMATION METHOD, AND TRANSISTOR MANUFACTURING METHOD 株式会社ニコン 2024-02-29 WO disclosed
WO-2022138605-A1 METHOD FOR PRODUCING PEPTIDE, REAGENT FOR FORMING PROTECTIVE GROUP, AND FUSED POLYCYCLIC COMPOUND 富士フイルム株式会社 2022-06-30 WO disclosed
CN-114026110-A Method for producing peptide compound, protecting group-forming reagent, and fused polycyclic compound 富士胶片株式会社 2022-02-08 CN disclosed
EP-3489245-B1 NEW XANTHENE PROTECTIVE AGENT SEKISUI MEDICAL CO LTD (JP) 2020-10-14 EP disclosed
US-20190263842-A1 NEW XANTHENE PROTECTIVE AGENT SEKISUI MEDICAL CO., LTD. (JP) 2019-08-29 US disclosed
EP-3489245-A1 NEW XANTHENE PROTECTIVE AGENT Sekisui Medical Co., Ltd. (JP) 2019-05-29 EP disclosed
US-8084643-B2 Nitrogen-containing esters of the secondary alcohol group of florfenicol and of its analogs,including salts; veterinary medicine; nonhydrolyzing as needed to maintain the prodrug in aqueous solution in the subjects system until appropriate; cattle drinking water; bovine respiratory disease INTERVET INC. (US) 2011-12-27 US disclosed
US-8044230-B2 Hydrolytic stability needed to maintain the prodrug in solution in the subject's system until appropriate conditions exist when the prodrug can hydrolyze, releasing the active compound INTERVET INC. (US) 2011-10-25 US disclosed
EP-2102154-A1 WATER-SOLUBLE PRODRUGS OF CHLORAMPHENICOL, THIAMPHENICOL, AND ANALOGS THEREOF Schering-Plough Ltd. (CH) 2009-09-23 EP disclosed
US-6596743-B2 Control or prevention of acute and/or chronic neurological disorders HOFFMANN-LA ROCHE INC. 2003-07-22 US disclosed
WO-2003038092-A1 METHOD FOR IDENTIFYING TRANSPORT PROTEINS SYMPORE GMBH (DE) 2003-05-08 WO disclosed
US-6462198-B1 USED IN THE CONTROL OR PREVENTION OF ACUTE AND/OR CHRONIC NEUROLOGICAL DISORDERS SUCH AS RESTRICTED BRAIN FUNCTION CAUSED BY BYPASS OPERATIONS OR TRANSPLANTS, POOR BLOOD SUPPLY TO THE BRAIN, SPINAL CORD INJURIES, HEAD INJURIES, HYPOXIA, HOFFMANN-LA ROCHE INC. 2002-10-08 US disclosed
US-20020091150-A1 Carbamic acid derivatives BLEICHER KONRAD (DE) 2002-07-11 US disclosed
EP-1171423-A1 CARBAMIC ACID DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 2002-01-16 EP disclosed
WO-2000063166-A1 CARBAMIC ACID DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 2000-10-26 WO disclosed
US-4547492-A 1-N-(ω-Amino-α-hydroxyalkanoyl-2',3'-dideoxykanamycin A and pharmaceutical composition containing same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-10-15 US disclosed
EP-0139553-A2 1N-(omega-amino-alpha-hydroxyalkanoyl)-2',3'-dideoxykanamycin A and the production of the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-05-02 EP disclosed
US-4248786-A Hydroxy-succinimide ester compounds BOEHRINGER MANNHEIM GMBH (DE) 1981-02-03 US disclosed
US-4155914-A Hydroxy-succinimide ester compounds BOEHRINGER MANNHEIM GMBH (DE) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250180990-A1 PHOTOSENSITIVE SURFACE TREATING AGENT, LAMINATE, PATTERN FORMATION SUBSTRATE, TRANSISTOR, PATTERN FORMING METHOD AND METHOD OF PRODUCING TRANSISTOR CHRM1, LMNB1, CCNT1 MAP3K14 2673/4885CRBN 2765/4885DDB1 1054/4885
US-20020091150-A1 Carbamic acid derivatives CHRM1, CHRNA2, CHRM2 MAP3K14 2757/4885CRBN 3545/4885DDB1 978/4885
US-20190263842-A1 NEW XANTHENE PROTECTIVE AGENT XDH, XPA, XPO7 MAP3K14 1398/4885CRBN 1082/4885DDB1 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.