Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL11082339 | 0.98 | MAP3K14 (0.39) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL5318696 | 0.84 | NPC1 (0.44) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL28153842 | 0.80 | NPC1 (0.48) | MAP3K14NPC1CRBNDDB1LMNA | |
| Methane SCHEMBL27666784 | 0.78 | NPC1 (0.47) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL27597851 | 0.78 | NPC1 (0.47) | NPC1CRBNDDB1LMNAMAPT | |
| Butane SCHEMBL11090167 | 0.78 | NPC1 (0.41) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL1034864 | 0.76 | — | — | |
| SCHEMBL10754755 | 0.75 | MAP3K14 (0.48) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL8348991 | 0.75 | MAP3K14 (0.48) | MAP3K14NPC1CRBNDDB1LMNA | |
| SCHEMBL114367 | 0.75 | NPC1 (0.36) | MAP3K14NPC1CRBNDDB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316438-B1 | CHEMICAL PREVENTION OR REVERSAL OF CATARACT BY PHASE SEPARATION INHIBITORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1993-09-01 | — | — | EP | claimed |
| CN-107406363-A | The manufacture method of (methyl) acrylate | 东亚合成株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-102015281-A | Laminated fabric construction with heat activated polyurethaneurea compositions | INVISTA TECH SARL | 2011-04-13 | — | — | CN | disclosed |
| CN-1206222-C | Process for preparing N-hydroxyalkyl compound and isocynauric acid tri (2-ethoyl) ester composition | NIPPON CATALYTIC CHEM IND (JP) | 2005-06-15 | — | — | CN | disclosed |
| CN-1428331-A | Process for preparing N-hydroxyalkyl compound and isocynauric acid tri (2-ethoyl) ester composition | NIPPON CATALYTIC CHEM IND (JP) | 2003-07-09 | — | — | CN | disclosed |