Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756419 | 0.96 | EPHX1 (0.47) | USP2ATMPTPN7EPHX2HTT | |
| SCHEMBL10755892 | 0.95 | EPHX1 (0.49) | EPHX2HTTSMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL10756172 | 0.95 | EPHX1 (0.49) | EPHX2HTTSMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL10754708 | 0.92 | PTPN7 (0.43) | USP2PTPN7GAAPOLBMEN1 | |
| SCHEMBL10757205 | 0.82 | GAA (0.45) | GAAPOLBMEN1KMT2AHTT | |
| SCHEMBL10756733 | 0.81 | RAB9A (0.55) | PTPN7POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10756747 | 0.79 | KDM4C (0.43) | PTPN7GAAPOLBKMT2AHTT | |
| SCHEMBL10758718 | 0.78 | RAB9A (0.43) | USP2MEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL10757877 | 0.77 | ALDH1A1 (0.50) | PTPN7GAAPOLBMEN1KMT2A | |
| SCHEMBL10756983 | 0.76 | KDM4C (0.41) | USP2GAAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |