Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754708 | 0.84 | PTPN7 (0.43) | GAATP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL10756983 | 0.82 | KDM4C (0.41) | GAALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10756902 | 0.82 | USP2 (0.46) | GAASMN1; SMN2HTTHPGDPOLB | |
| SCHEMBL10756747 | 0.82 | KDM4C (0.43) | GAATP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL10758718 | 0.82 | RAB9A (0.43) | LMNASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL10756419 | 0.81 | EPHX1 (0.47) | LMNASMN1; SMN2HTTTDP1ALDH1A1 | |
| SCHEMBL10757877 | 0.81 | ALDH1A1 (0.50) | GAATP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL10755892 | 0.80 | EPHX1 (0.49) | LMNASMN1; SMN2HTTTDP1ALDH1A1 | |
| SCHEMBL10756172 | 0.80 | EPHX1 (0.49) | LMNASMN1; SMN2HTTTDP1ALDH1A1 | |
| SCHEMBL10756733 | 0.79 | RAB9A (0.55) | LMNASMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |