Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757401 | 0.83 | PDE10A (0.41) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL2192308 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL28543507 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL8826783 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL1706586 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL10757404 | 0.80 | MAPT (0.41) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL28543509 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL9443208 | 0.78 | LMNA (0.41) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL9443308 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB | |
| SCHEMBL10644844 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HSD17B10MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696763-A | PAINTS, BLENDS | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |