Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758939 | 0.84 | LMNA (0.52) | LMNATSHRNPSR1ALDH1A1MEN1 | |
| SCHEMBL10764513 | 0.84 | HTR1A (0.55) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL10759933 | 0.81 | ALDH1A1 (0.56) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL8686716 | 0.81 | LMNA (0.52) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL8957656 | 0.78 | LMNA (0.55) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL30767206 | 0.78 | TSHR (0.57) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL29204363 | 0.78 | TSHR (0.57) | LMNATSHRMAPK1RECQLNPSR1 | |
| Hydrochloric Acid SCHEMBL10372885 | 0.75 | LMNA (0.54) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL8685769 | 0.75 | LMNA (0.52) | LMNATSHRMAPK1RECQLNPSR1 | |
| SCHEMBL4255355 | 0.73 | ALDH1A1 (0.59) | LMNAHTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711885-A | N-(N'-phenylpiperazine)-alkyl triazole compounds having anxiolytic and analgesic properties | ADIR ET COMPAGNIE (FR) | 1987-12-08 | — | — | US | disclosed |
| US-4575555-A | ANTIDEPRESSANTS | MEAD JOHNSON & COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| US-4487773-A | ANTISEROTONINE AGENTS | MEAD JOHNSON & COMPANY (US) | 1984-12-11 | — | — | US | disclosed |