Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.56 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253167 | 0.84 | GABRA1 (0.56) | NR1H4SLC2A1NPC1RAB9AGABRB1 | |
| SCHEMBL4262289 | 0.84 | GABRA1 (0.56) | NR1H4SLC2A1NPC1RAB9AGABRB1 | |
| SCHEMBL10758161 | 0.83 | GABRB2 (0.52) | NR1H4SLC2A1SLC2A2GABRB1GABRA2 | |
| SCHEMBL4258953 | 0.82 | GABRA1 (0.52) | NR1H4NPC1RAB9AGABRB1GABRA2 | |
| SCHEMBL13970090 | 0.82 | GABRA1 (0.54) | NR1H4NPC1RAB9AGABRB1GABRA2 | |
| SCHEMBL3036183 | 0.82 | SLC2A1 (0.47) | SLC2A1SLC2A2GABRA2GABRB2ALB | |
| SCHEMBL4253077 | 0.81 | GABRA1 (0.58) | NR1H4SLC2A1NPC1RAB9AGABRB1 | |
| SCHEMBL4257110 | 0.81 | TP53 (0.54) | NR1H4NPC1RAB9AGABRB1GABRA2 | |
| SCHEMBL4255844 | 0.81 | GABRA1 (0.53) | NPC1RAB9AGABRB1GABRA2GABRB2 | |
| SCHEMBL4260996 | 0.81 | GABRA1 (0.50) | NR1H4SLC2A1NPC1RAB9AGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650796-A | ANXIOLYTIC, HYPNOTIC, ANTICONVULSANT, ANALGESIC, ANTIULCER | SYNTHELABO (FR) | 1987-03-17 | — | — | US | disclosed |