Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754545 | 0.89 | ALB (0.51) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL10758271 | 0.83 | NR1H4 (0.57) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL10758241 | 0.82 | ALB (0.53) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL4261039 | 0.80 | GABRA1 (0.57) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL14889249 | 0.79 | GABRB2 (0.65) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL4255619 | 0.79 | GABRA1 (0.56) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL1691376 | 0.79 | ALDH1A1 (0.58) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL4262267 | 0.78 | KDM4E (0.60) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL4261710 | 0.77 | GABRA1 (0.59) | GABRB2ALBOPRK1KCNH2GABRA1 | |
| SCHEMBL4264310 | 0.76 | GABRA1 (0.61) | GABRB2ALBOPRK1KCNH2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650796-A | ANXIOLYTIC, HYPNOTIC, ANTICONVULSANT, ANALGESIC, ANTIULCER | SYNTHELABO (FR) | 1987-03-17 | — | — | US | disclosed |