SCHEMBL10758570

SCHEMBL10758570

ClC[CH]Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.39
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.39
CA4 P22748 1/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
AOC3 Q16853 1/20 0.34
ALOX15 P16050 1/20 0.33
RNF4 P78317 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
TTR P02766 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11559191 0.76 LTA4H (0.42) LTA4HTSHRKCNA3CA4NR1H2
SCHEMBL10611874 0.75 LTA4H (0.39) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL98246 0.75 CA4 (0.42) LTA4HTSHRKCNA3CA4LMNA
SCHEMBL8134399 0.75 KCNA3 (0.44) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL1679226 0.75 LTA4H (0.46) LTA4HTSHRKCNA3CA4NR1H2
SCHEMBL2650170 0.73 AOC3 (0.52) LTA4HTSHRKCNA3TAAR1ALDH1A1
SCHEMBL1070130 0.73 MAOB (0.50) LTA4HTSHRKCNA3ALDH1A1DRD2
SCHEMBL7950288 0.73 TSHR (0.38) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL8623766 0.72 LTA4H (0.41) LTA4HTSHRKCNA3CA4NR1H2
SCHEMBL8623765 0.72 LTA4H (0.41) LTA4HTSHRKCNA3CA4NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4695632-A ANIONIC DYE AFFINITY BAYER AKTIENGESELLSCHAFT (DE) 1987-09-22 US disclosed
US-4362874-A PYRIMIDINES, ANIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1982-12-07 US disclosed
US-4212803-A Cationic azo dyestuffs containing oxyalkylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4122257-A Benzofuran-oxadiazole compounds HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed