SCHEMBL98246

SCHEMBL98246

CC[CH]Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 5/20 0.41
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.39
CHRNB2 P17787 2/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA7 P36544 2/20 0.38
CHRNA4 P43681 2/20 0.38
RELA Q04206 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23581950 0.87 CHRNB2 (0.43) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL22769298 0.82 RXRA (0.44) LTA4H
SCHEMBL100407 0.81 LTA4H (0.41) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL2782678 0.78 ACHE (0.44) TSHRRELAL3MBTL1LMNA
SCHEMBL6763475 0.78 CA1 (0.52) LTA4HTSHRL3MBTL1TP53LMNA
SCHEMBL652685 0.78 LTA4H (0.47) CA4LTA4HKCNA3LMNA
SCHEMBL12492306 0.76 CYP3A4 (0.38) TSHRLMNA
SCHEMBL8220198 0.76 CA4 (0.44) CA4LTA4HTSHRKCNA3LMNA
SCHEMBL712372 0.76 HTR2A (0.37) TSHRLMNA
SCHEMBL7494621 0.76 NFE2L2 (0.42) TSHRL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2343 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11998621-B2 Transparent, fracture-tough polymerization resins for the production of dental shaped bodies IVOCLAR VIVADENT AG (LI) 2024-06-04 US claimed
EP-4329881-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF Vanqua Bio, Inc. (US) 2024-03-06 EP claimed
CN-117642404-A Small molecule modulators of glucocerebrosidase activity and uses thereof 凡况生化公司 2024-03-01 CN claimed
CN-117624029-A Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine 赣江中药创新中心 2024-03-01 CN claimed
EP-4061864-B1 ONE COMPONENT (1K) ANAEROBIC CURABLE COMPOSITION HENKEL AG & CO KGAA (DE) 2023-10-18 EP claimed
CN-115300400-A Transparent, fracture-tough polymeric resins for the production of dental molded bodies 义获嘉伟瓦登特公司 2022-11-08 CN claimed
CN-114667304-A One-component (1K) anaerobically curable compositions 汉高股份有限及两合公司 2022-06-24 CN claimed
US-20220135557-A1 RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-05-05 US claimed
US-20220119382-A1 RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-04-21 US claimed
CN-113683611-A RET inhibitors, pharmaceutical compositions thereof and uses thereof 广东东阳光药业有限公司 2021-11-23 CN claimed
EP-0051187-A2 Cationic styryl dyes, their preparation and their use in dying basic dyeable natural or synthetic substrates BAYER AG (DE) 1982-05-12 EP claimed
US-4264494-A Chromium complex dyestuffs for natural polyamides and synthetic nylons BASF AKTIENGESELLSCHAFT (DE) 1981-04-28 US claimed
US-4212801-A Unsymmetrical 1:2-chromium complexes containing an azo and an azomethine bond BASF AKTIENGESELLSCHAFT (DE) 1980-07-15 US claimed
US-4168263-A HAVING PENICILLOYL RESIDUES BOUND TO SIDE CHAINS HOFFMANN-LA ROCHE INC. (US) 1979-09-18 US claimed
US-4046572-A SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-09-06 US claimed
US-4024272-A Tetracyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-05-17 US claimed
US-4016152-A SUITABLE FOR DYEING POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1977-04-05 US claimed
US-4004927-A Photographic light-sensitive material containing liquid organopolysiloxane FUJI PHOTO FILM CO., LTD. (JA) 1977-01-25 US claimed
US-3993643-A ANTISCHISTOSOMAL STANFORD RESEARCH INSTITUTE (US) 1976-11-23 US claimed
US-3974123-A Dyes for thermoplastics BASF AKTIENGESELLSCHAFT (DT) 1976-08-10 US claimed