Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394332 | 0.79 | TYMP (0.54) | TYMPMAPTPKMADORA3XDH | |
| SCHEMBL10394333 | 0.70 | TYMP (0.46) | TYMPADORA3ALDH1A1BACE1LMNA | |
| SCHEMBL12515629 | 0.69 | TYMP (0.68) | TYMPMAPTPKMALDH1A1LMNA | |
| SCHEMBL18486353 | 0.66 | TYMP (0.87) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL29673058 | 0.66 | TYMP (0.87) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL28632187 | 0.66 | TYMP (0.68) | TYMPADORA3 | |
| SCHEMBL20691415 | 0.66 | TYMP (1.00) | TYMP | |
| SCHEMBL10394926 | 0.66 | TYMP (0.51) | TYMPADORA3ALDH1A1LMNAALB | |
| SCHEMBL21878002 | 0.65 | TYMP (0.50) | TYMPMAPTPKMADORA3XDH | |
| SCHEMBL10394454 | 0.65 | TYMP (0.44) | TYMPADORA3XDHSLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |