Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394926 | 0.84 | TYMP (0.51) | TYMPADORA3ALDH1A1LMNAALB | |
| SCHEMBL10394332 | 0.82 | TYMP (0.54) | TYMPADORA3ALDH1A1BACE1 | |
| SCHEMBL10394453 | 0.74 | TYMP (0.44) | TYMPADORA3PNP | |
| SCHEMBL10394454 | 0.74 | TYMP (0.44) | TYMPADORA3PNP | |
| SCHEMBL10394457 | 0.72 | PNP (0.40) | TYMPADORA3PNP | |
| SCHEMBL10696433 | 0.71 | TYMP (0.41) | TYMP | |
| SCHEMBL10759491 | 0.70 | TYMP (0.49) | TYMPADORA3ALDH1A1LMNAALB | |
| SCHEMBL10394925 | 0.69 | TYMP (0.38) | TYMPALDH1A1 | |
| SCHEMBL10696436 | 0.68 | TYMP (0.36) | TYMPTK1 | |
| SCHEMBL12515629 | 0.66 | TYMP (0.68) | TYMPALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |