Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197020 | 0.81 | DPP4 (0.52) | CD274PDCD1DPP4HTR7KMT2A | |
| SCHEMBL2841431 | 0.80 | DPP4 (0.65) | CD274PDCD1DPP4HTR7KMT2A | |
| SCHEMBL31387875 | 0.80 | DPP4 (0.65) | CD274PDCD1DPP4HTR7KMT2A | |
| SCHEMBL27857549 | 0.76 | DPP4 (0.40) | CD274PDCD1DPP4HTR7KMT2A | |
| SCHEMBL7990271 | 0.75 | CALM1 (0.46) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL1838644 | 0.74 | HSPA5 (0.61) | KMT2ACA12CA2ALDH1A1TSHR | |
| SCHEMBL11199829 | 0.73 | P2RX7 (0.39) | CD274PDCD1CA12CA1CA9 | |
| SCHEMBL30804714 | 0.72 | ESR2 (0.48) | CD274PDCD1KMT2ACYP2A6CYP2B6 | |
| SCHEMBL2400343 | 0.72 | ESR2 (0.48) | CD274PDCD1KMT2ACYP2A6CYP2B6 | |
| SCHEMBL17923250 | 0.71 | CA12 (0.48) | CD274PDCD1DPP4HTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710529-A | DISCOLORATION INHIBITION, IMPACT STRENGTH | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-01 | — | — | US | disclosed |