Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444857 | 0.81 | KMT2A (0.47) | HTTTSHRALDH1A1NPSR1 | |
| SCHEMBL28709691 | 0.79 | HTT (0.48) | HTTNAPRTTBXAS1TRPV1KEAP1 | |
| SCHEMBL13153186 | 0.78 | CHRNB2 (0.44) | HTTTRPV1KCNA5RIPK1KCNN4 | |
| SCHEMBL4066046 | 0.76 | HTT (0.44) | HTTNAPRTGAATSHRKCNA5 | |
| SCHEMBL12057237 | 0.73 | CHRNB2 (0.35) | HTTTRPV1KCNA5RIPK1KCNN4 | |
| SCHEMBL9080141 | 0.72 | ALDH1A1 (0.45) | HTTGAATSHRALDH1A1MAPT | |
| SCHEMBL16586311 | 0.71 | HTT (0.43) | HTTNAPRTTRPV1GAATSHR | |
| SCHEMBL17591681 | 0.70 | CYP3A4 (0.43) | HTTTRPV1GAATSHRKCNA5 | |
| SCHEMBL6671752 | 0.70 | HTT (0.65) | HTTNAPRTTRPV1GAATSHR | |
| SCHEMBL9078636 | 0.70 | NR1H4 (0.47) | KEAP1NFE2L2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686295-A | N-carboxy anhydride intermediates | USV PHARMACEUTICAL CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |