Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444857 | 0.89 | KMT2A (0.47) | ALDH1A1TSHRHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9078636 | 0.81 | NR1H4 (0.47) | ALDH1A1LMNATSHRMAPTSMN1; SMN2 | |
| SCHEMBL10354379 | 0.78 | KEAP1 (0.54) | MEN1KMT2A | |
| SCHEMBL16858007 | 0.77 | KMT2A (0.46) | ALDH1A1TSHRHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL14067916 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EUSP2LMNAABCC4 | |
| SCHEMBL13644999 | 0.76 | LMNA (0.50) | ALDH1A1KDM4EUSP2LMNAABCC4 | |
| SCHEMBL21874427 | 0.74 | KMT2A (0.43) | ALDH1A1TSHRHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7398832 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4EUSP2LMNAABCC4 | |
| SCHEMBL6607125 | 0.73 | GSTO1 (0.42) | ALDH1A1KDM4EUSP2LMNAABCC4 | |
| SCHEMBL29085123 | 0.72 | CA1 (0.41) | ALDH1A1GAATSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |