Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764444 | 0.84 | HSD17B10 (0.40) | MAPTSMN1; SMN2GPR119PDE3APDE3B | |
| SCHEMBL10765553 | 0.82 | PTGS2 (0.37) | GPR119PDE3APDE3BPDE4BPTGS2 | |
| SCHEMBL10761023 | 0.81 | MAOB (0.44) | MAPTSMN1; SMN2PDE3APDE3BPTGS2 | |
| SCHEMBL10764678 | 0.80 | PDE3B (0.43) | MAPTSMN1; SMN2GPR119CA12CA2 | |
| SCHEMBL10762324 | 0.80 | MAOB (0.43) | GPR119CA12CA2CA9PDE3A | |
| SCHEMBL10764370 | 0.80 | PDE3B (0.34) | MAPTSMN1; SMN2GPR119PDE3APDE3B | |
| SCHEMBL10767881 | 0.80 | MAPT (0.39) | MAPTSMN1; SMN2GPR119PDE3APDE3B | |
| SCHEMBL10762076 | 0.75 | PBRM1 (0.36) | MAPTSMN1; SMN2GPR119PDE3APDE3B | |
| SCHEMBL10763440 | 0.74 | PDE3A (0.40) | MAPTSMN1; SMN2GPR119PDE3APDE3B | |
| SCHEMBL10762863 | 0.74 | BRD4 (0.41) | MAPTSMN1; SMN2GPR119PDE3APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |