Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765732 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10764037 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10761709 | 0.80 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10766091 | 0.80 | RAB9A (0.62) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10765745 | 0.80 | RAB9A (0.62) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10766477 | 0.78 | PTGS1 (0.64) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10759477 | 0.78 | PTGS1 (0.64) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10760986 | 0.78 | PTGS2 (0.64) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10762417 | 0.78 | PTGS2 (0.64) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10760671 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |