Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761709 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10760256 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10765726 | 0.78 | RAB9A (0.55) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10761671 | 0.77 | PTGS1 (0.54) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10763296 | 0.77 | PDE3A (0.43) | PTGS2PTGS1GAAPDE3BPDE3A | |
| SCHEMBL10766800 | 0.77 | PTGS1 (0.54) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10766427 | 0.76 | PTGS1 (0.59) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10763618 | 0.76 | PTGS2 (0.67) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10767198 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10765262 | 0.74 | PTGS2 (0.52) | PTGS2PTGS1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |