Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660150 | 0.91 | CES2 (0.64) | ESR1ESR2LMNARAB9AMAPT | |
| SCHEMBL22345808 | 0.89 | CES2 (0.61) | ESR1ESR2LMNARAB9AMAPT | |
| Hydroquinone SCHEMBL18144646 | 0.89 | CES2 (0.60) | ESR1ESR2LMNARAB9AMAPT | |
| SCHEMBL3292238 | 0.89 | PDCD1 (0.62) | LMNARAB9AMAPTPDCD1CD274 | |
| SCHEMBL3292249 | 0.87 | PDCD1 (0.60) | LMNARAB9AMAPTMEN1KMT2A | |
| Biphenyl SCHEMBL7862554 | 0.87 | F2 (0.61) | LMNARAB9AMAPTKMT2ACES2 | |
| SCHEMBL5669277 | 0.87 | CA1 (0.65) | ESR1ESR2LMNAMAPTMEN1 | |
| Biphenyl SCHEMBL27469149 | 0.84 | CA1 (0.77) | ESR1ESR2LMNARAB9AMAPT | |
| SCHEMBL8717537 | 0.82 | LMNA (0.67) | LMNAMAPTKMT2ACES2KDM4E | |
| SCHEMBL19666759 | 0.82 | MAPT (0.62) | LMNARAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229777-A1 | NOVEL POLY(ARYL ETHER KETONES) | AMOCO CORPORATION (US) | 1987-07-29 | — | — | EP | claimed |
| WO-1986007599-A1 | NOVEL POLY(ARYL ETHER KETONES) | AMOCO CORPORATION (US) | 1986-12-31 | — | — | WO | claimed |