SCHEMBL3292249

SCHEMBL3292249

O=C(OC(=O)c1ccc(-c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.60
CD274 Q9NZQ7 1/20 0.60
RAB9A P51151 3/20 0.57
NPC1 O15118 1/20 0.57
CTDSP1 Q9GZU7 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 1/20 0.56
LMNA P02545 3/20 0.56
F2 P00734 1/20 0.56
MAPT P10636 3/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
TSHR P16473 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
PTPN1 P18031 2/20 0.51
SLC1A5 Q15758 1/20 0.51
GSK3B P49841 1/20 0.50
EGFR P00533 1/20 0.50
CDC25B P30305 1/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292238 0.98 PDCD1 (0.62) PDCD1CD274RAB9ANPC1CTDSP1
Biphenyl SCHEMBL7862554 0.95 F2 (0.61) PDCD1CD274RAB9ANPC1CTDSP1
SCHEMBL19666759 0.94 MAPT (0.62) PDCD1CD274RAB9ANPC1CTDSP1
Ethyne SCHEMBL28750829 0.91 LMNA (0.56) PDCD1CD274RAB9ANPC1CTDSP1
SCHEMBL8717537 0.91 LMNA (0.67) SMN1; SMN2KDM4ELMNAF2MAPT
SCHEMBL52413 0.88 LMNA (0.70) SMN1; SMN2LMNAF2MAPTL3MBTL1
Benzene SCHEMBL27793442 0.88 LMNA (0.70) SMN1; SMN2LMNAF2MAPTL3MBTL1
Hydrogen Peroxide SCHEMBL27952375 0.88 LMNA (0.70) SMN1; SMN2LMNAF2MAPTL3MBTL1
SCHEMBL28073554 0.88 CYP1A2 (0.58) PDCD1CD274SMN1; SMN2KDM4EMAPT
Biphenyl SCHEMBL10761998 0.87 ESR1 (0.59) PDCD1CD274RAB9ANPC1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN claimed
CN-105218372-A (4-Phenylbenzoyl) benzoic ether and the purposes as light trigger thereof INSIGHT HIGH TECHNOLOGY BEIJING CO LTD 2016-01-06 CN claimed
CN-103429680-B Radiation curable compositions ALLNEX Belgium SA 2015-06-17 CN claimed
CN-103443215-A Radiation curable compositions ALLNEX Belgium SA 2013-12-11 CN claimed
CN-103429680-A Radiation curable compositions ALLNEX Belgium SA 2013-12-04 CN claimed
EP-4437048-B1 ENERGY CURABLE INK, COATING AND PRIMER COMPOSITIONS CONTAINING HIGHLY ALKOXYLATED GLYCEROL ACRYLATES FOR RETORT PACKAGING APPLICATIONS SUN CHEMICAL BV (NL) 2026-02-25 EP disclosed
CN-119191950-A Asymmetric diaryl ketone compound and synthetic method thereof 海南大学 2024-12-27 CN disclosed
EP-3134379-B1 LIQUID ARYLBENZOYL BENZOIC ACID ESTER DERIVATIVES FOR ENERGY CURABLE COMPOSITIONS SUN CHEMICAL BV (NL) 2024-08-28 EP disclosed
CN-111936136-B Novel imidazopyrimidine compounds and uses thereof 儿童医学中心公司 2024-07-05 CN disclosed
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN disclosed
US-9938231-B2 Liquid arylbenzoyl benzoic acid ester derivatives for energy curable compositions SUN CHEMICAL CORPORATION (US) 2018-04-10 US disclosed
US-9938231-B2 Liquid arylbenzoyl benzoic acid ester derivatives for energy curable compositions SUN CHEMICAL CORPORATION (US) 2018-04-10 US disclosed
CN-103429680-A Radiation curable compositions ALLNEX Belgium SA 2013-12-04 CN disclosed
CN-103429679-A Radiation curable compositions CYTEC SURFACE SPECIALTIES SA 2013-12-04 CN disclosed
US-7727434-B2 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY (US) 2010-06-01 US disclosed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US disclosed
US-20030181742-A1 Process for the preparation of pregnane derivatives KURARAY CO., LTD. (JP) 2003-09-25 US disclosed
EP-1325928-A1 PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES Kuraray Co., Ltd. (JP) 2003-07-09 EP disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-4988460-A HYDROGEN BONDED ADDITION POLYMERS, POLYCARBONATES, POLYESTERS, OR POLYAMIDES, AROMATIC ESTER DERIVATIVES AS LIQUID CRYSTALS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181742-A1 Process for the preparation of pregnane derivatives CYP21A2, CYP11B2, CYP17A1 PDCD1 3509/4885CD274 4257/4885RAB9A 4281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.