Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742659 | 0.80 | TSHR (0.48) | TSHRALDH1A1HSD17B10USP2SMN1; SMN2 | |
| SCHEMBL10741199 | 0.80 | USP2 (0.57) | TSHRALDH1A1USP2SMN1; SMN2TDP1 | |
| SCHEMBL10743331 | 0.79 | ATM (0.49) | TSHRALDH1A1SMN1; SMN2PDE7ATDP1 | |
| SCHEMBL10742059 | 0.76 | PDE7A (0.45) | TSHRALDH1A1USP2PTGS2SMN1; SMN2 | |
| SCHEMBL10739938 | 0.72 | TDP1 (0.57) | TSHRALDH1A1HSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL10737433 | 0.71 | TDP1 (0.64) | TSHRALDH1A1HSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL10741723 | 0.68 | CYP3A4 (0.50) | TSHRUSP2SMN1; SMN2TDP1POLB | |
| SCHEMBL10733928 | 0.67 | PDE7A (0.49) | TSHRALDH1A1PTGS2SMN1; SMN2PDE7A | |
| SCHEMBL24754223 | 0.64 | USP5 (0.50) | TSHRHSD17B10SMN1; SMN2POLBKDM4E | |
| SCHEMBL6248101 | 0.64 | USP2 (0.62) | TSHRALDH1A1USP2SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |