Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761951 | 0.87 | NPC1 (0.48) | PDE3BPDE3ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10765345 | 0.83 | PDE3B (0.56) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10763419 | 0.80 | PDE3B (0.43) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10765188 | 0.79 | PDE3B (0.56) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10763162 | 0.79 | GPR119 (0.41) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10761737 | 0.79 | PDE3B (0.67) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10764072 | 0.78 | PDE3B (0.57) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10759796 | 0.77 | PDE3B (0.69) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL10761194 | 0.77 | PDE3B (0.65) | PDE3BPDE3ARAB9AMAPTNPC1 | |
| SCHEMBL7285568 | 0.77 | PDE3B (0.65) | PDE3BPDE3ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |