Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764383 | 1.00 | LMNA (0.63) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10766290 | 0.90 | APP (0.70) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10766293 | 0.90 | APP (0.70) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10764094 | 0.88 | LMNA (0.68) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10764099 | 0.88 | LMNA (0.68) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10766353 | 0.82 | LMNA (0.60) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10766356 | 0.82 | LMNA (0.60) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL9553254 | 0.81 | MMP9 (0.80) | APPPTGS2MAPTMMP9ALOX5 | |
| SCHEMBL10763650 | 0.81 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL10763653 | 0.81 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |