SCHEMBL1076444

SCHEMBL1076444

Fc1cccc(Oc2ccccc2)c1P(Br)Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.44
SLC6A2 P23975 2/20 0.44
HTR1A P08908 1/20 0.44
SLC6A3 Q01959 1/20 0.44
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HRH1 P35367 1/20 0.40
PARP10 Q53GL7 1/20 0.39
TSHR P16473 2/20 0.38
LTA4H P09960 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
FAAH O00519 1/20 0.38
KDM1A O60341 2/20 0.38
DPP4 P27487 1/20 0.38
HTR2A P28223 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CTNNB1 P35222 1/20 0.36
RIPK1 Q13546 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1076443 1.00 SLC6A4 (0.44) SLC6A4SLC6A2HTR1ASLC6A3TDP1
SCHEMBL1040163 0.82 SLC6A4 (0.44) SLC6A4SLC6A2HTR1ASLC6A3TDP1
SCHEMBL1042524 0.78 LTA4H (0.38) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL702582 0.76 PARP10 (0.58) SLC6A4SLC6A2HTR1ASLC6A3TDP1
SCHEMBL1042653 0.76 NFE2L2 (0.43) TDP1L3MBTL1TSHRLMNAKMT2A
SCHEMBL16890475 0.76 SLC6A4 (0.47) SLC6A4SLC6A2HTR1ASLC6A3TDP1
SCHEMBL7732234 0.75 SLC6A4 (0.50) SLC6A4SLC6A2HTR1ASLC6A3TDP1
Ammonia Solution, Strong SCHEMBL4266595 0.74 PARP10 (0.56) SLC6A4SLC6A2HTR1ASLC6A3TDP1
SCHEMBL6288573 0.74 LTA4H (0.50) SLC6A4SLC6A2HTR1ASLC6A3L3MBTL1
SCHEMBL1039758 0.73 CES2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
EP-2272852-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex Sumitomo Chemical Company, Limited (JP) 2011-01-12 EP disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
EP-1683802-A1 TRANSITION METAL COMPLEX LIGAND AND OLEFIN POLYMERIZATION CATALYST CONTAINING TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 SLC6A4 3977/4885SLC6A2 4283/4885HTR1A 3078/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 SLC6A4 3977/4885SLC6A2 4283/4885HTR1A 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.