Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764318 | 0.85 | PDE3B (0.57) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10765618 | 0.85 | PDE3B (0.54) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10764414 | 0.85 | PDE3B (0.54) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10763204 | 0.84 | PDE3B (0.51) | PDE3BPDE3AMAOBNFE2L2PTGS1 | |
| SCHEMBL10761216 | 0.84 | PDE3B (0.65) | PDE3BPDE3AMAOBNFE2L2 | |
| SCHEMBL10766164 | 0.82 | PDE3B (0.52) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10767320 | 0.81 | CREBBP (0.53) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10763316 | 0.81 | PDE3B (0.50) | PDE3BPDE3AMAOBPTGS1PTGS2 | |
| SCHEMBL10762047 | 0.79 | RELA (0.56) | PDE3BPDE3ANFE2L2APPRELA | |
| SCHEMBL10761951 | 0.77 | NPC1 (0.48) | PDE3BPDE3APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |