Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763903 | 0.87 | PDE3B (0.47) | PDE3BPDE3AALDH1A1PBRM1POLB | |
| SCHEMBL10765802 | 0.83 | PDE3B (0.55) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10761240 | 0.83 | PDE3B (0.62) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10764122 | 0.81 | PDE3A (0.46) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10761200 | 0.81 | PDE3A (0.46) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10768068 | 0.81 | PDE3B (0.40) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10763296 | 0.80 | PDE3A (0.43) | PDE3BPDE3AGAAALDH1A1PBRM1 | |
| SCHEMBL10760541 | 0.79 | PDE3B (0.56) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10761515 | 0.79 | PDE3B (0.38) | PDE3BPDE3AGAAALDH1A1MAPT | |
| SCHEMBL10761737 | 0.79 | PDE3B (0.67) | PDE3BPDE3AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |