SCHEMBL1076548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1032599	0.86	POLQ (0.50)	POLQPHGDHNPC1RAB9ALMNA
	SCHEMBL1204609	0.86	POLQ (0.53)	POLQNPC1RAB9AALDH1A1L3MBTL1
	SCHEMBL1032671	0.86	POLQ (0.47)	POLQPHGDHNPC1RAB9AMEN1
	SCHEMBL1035704	0.85	POLQ (0.51)	POLQNPC1RAB9AALDH1A1HPGD
	SCHEMBL1076488	0.85	POLQ (0.44)	POLQPHGDHNPC1RAB9AMAPT
	SCHEMBL1035037	0.85	LMNA (0.53)	POLQPHGDHNPC1RAB9ALMNA
	SCHEMBL1075258	0.85	RAB9A (0.47)	POLQNPC1RAB9AMAPTALDH1A1
	SCHEMBL1034084	0.84	ATR (0.45)	POLQNPC1RAB9AMAPTATR
	SCHEMBL1035334	0.83	POLQ (0.44)	POLQPHGDHNPC1RAB9AMAPT
	SCHEMBL1031618	0.83	LRRK2 (0.60)	NPC1RAB9ALMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.