Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530908 | 0.79 | DRD2 (0.38) | DRD2HTR1ADRD4 | |
| SCHEMBL10766377 | 0.70 | SIGMAR1 (0.35) | — | |
| SCHEMBL9528211 | 0.68 | DRD2 (0.52) | DRD2HTR1ADRD4 | |
| SCHEMBL9527512 | 0.66 | — | — | |
| SCHEMBL9528106 | 0.65 | — | — | |
| SCHEMBL9527015 | 0.65 | — | — | |
| SCHEMBL9527911 | 0.65 | HTR1A (0.58) | DRD2HTR1ADRD4 | |
| SCHEMBL11002569 | 0.64 | DRD2 (0.49) | DRD2HTR1ADRD4 | |
| SCHEMBL9526876 | 0.63 | HTR1A (0.48) | DRD2HTR1A | |
| SCHEMBL9759042 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |